mRNA precursors are processed in the spliceosome, where introns are excised to form continuous coding sequences. The major components of the spliceosome are RNA-protein complexes called snRNPs (small nuclear ribonucleoprotein particles). The core proteins that are common to all snRNPs are called the Sm proteins, and are designated B, B', D1, D2, D3, E, F and G. Antibodies recognizing Sm proteins are frequently generated in autoimmune diseases, including in patients with systemic lupus erythematosus. Sm proteins are characterized by a conserved Sm sequence motif in two parts, Sm1 and Sm2, which are separated by a variable region.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Sm B/B'/N (H-9) | sc-374078 | 200 µg/ml | $316.00 | |||
Sm B/B'/N (H-9): m-IgGκ BP-HRP Kit | sc-552022 | 200 µg Ab; 40 µg BP | $354.00 |