Anticorps SART-1 (F-4): sc-376288
- L'Anticorps SART-1 (F-4) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 107-406 situés près de la région N-terminus de SART-1 d'origine human
- recommandé pour la détection de SART-1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps SART-1 (F-4) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps SART-1 (F-4)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
SART-1 (squamous cell carcinoma antigen recognized by T cells), also known as Ara1, HOMS1 or Snu66, is a ubiquitously expressed protein that is involved in mRNA splicing and cell proliferation. The gene encoding SART-1 is posttranscriptionally modified to produce two proteins: SART-1(800), which is the native transcript and is localized to the nucleus of proliferating cells, and SART-1(259), which is expressed in the cytosol of epithelial cancers. While both proteins are involved in regulating cell proliferation, SART-1(259) is also an essential component in the spliceosome C assembly pathway playing a role in pre-mRNA splicing. SART-1(259) possesses a tumor-rejection antigen that can induce restricted cytotoxic T lymphocytes in cancer patients, suggesting a possible role in immunotherapy. Additionally, the polymorphic variation within the SART-1 gene may be a cause of atopy, an allergic hypersensitivity characterized by eczema, asthma and allergic conjunctivitis.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SART-1 (F-4) | sc-376288 | 200 µg/ml | $316.00 | |||
SART-1 (F-4): m-IgGκ BP-HRP Kit | sc-535481 | 200 µg Ab; 40 µg BP | $354.00 | |||
SART-1 (F-4): m-IgG2b BP-HRP Kit | sc-549426 | 200 µg Ab; 10 µg BP | $354.00 |