Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARα, RARβ and RARγ, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRα, RXRβ and RXRγ, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps RXRγ (G-6) | sc-514134 | 200 µg/ml | $316.00 | |||
RXRγ (G-6): m-IgG Fc BP-HRP Kit | sc-540960 | 200 µg Ab; 10 µg BP | $354.00 | |||
RXRγ (G-6): m-IgG1 BP-HRP Kit | sc-542493 | 200 µg Ab; 20 µg BP | $354.00 | |||
RXRγ (G-6) peptide neutralisant | sc-514134 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps RXRγ (G-6) X | sc-514134 X | 200 µg/0.1 ml | $316.00 |