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RRP9 (ribosomal RNA processing 9), also known as small subunit (SSU) processome component, RNU3IP2 or U355K, is a 475 amino acid nucleolar protein that belongs to the WD repeat RRP9 family. One of several components of a small nucleolar ribonucleoprotein particle (snoRNP), RRP9 is thought to be involved in the modification and processing of precursor rRNA (ribosomal RNA). Specifically, RRP9 interacts with the U3 snoRNA complex and binds a fragment of the complex that contains a box B/C motif and is known as 3UBC. The association of RRP9 with 3UBC is dependent upon two factors: binding of an snRNP protein known as NHPX to the B/C motif and a conserved tertiary structure that flanks the B/C motif. If the NHPK protein is bound and the conserved structure is present, RRP9 can interact with 3UBC and participate in pre-rRNA processing. RRP9 contains seven WD repeats that are necessary for both its nucleolar localization and its ability to bind U3 snoRNA.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps RRP9 (RS-9) | sc-100592 | 50 µg/0.5 ml | $316.00 |