Date published: 2025-9-8

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Anticorps RasGRP3 (B-1): sc-376745

5.0(1)
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Fiches techniques
  • L'Anticorps RasGRP3 (B-1) est un monoclonal de souris IgG3 (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 553-589 près de C-terminus de RasGRP3 d'origine human
  • recommandé pour la détection de RasGRP3 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • m-IgG3 BP-HRP est le réactif de détection secondaire préféré pour RasGRP3 Anticorps (B-1) pour les applications WB. Ce réactif est désormais proposé dans un ensemble avec RasGRP3 Anticorps (B-1)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Members of the Ras subfamily of GTPases function in signal transduction as GTP/GDP-modulated switches that rotate between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RasGRP3 (GRP3), act as Ras activators by promoting retrieval of GTP to maintain the active GTP-bound state and are the fundamental link between cell surface receptors and Ras activation. Highest levels of RasGRP3 expression are observed in heart, brain, lung and kidney tissues, and intermediate expression is observed in liver, skeletal muscle, pancreas, spleen, testis and ovary tissues. RasGRP3, which shares significant sequence identity with the calcium- and diacylglycerol-activated GEFs, activates Ras and Rap 1 and promotes activation of ELK1 in prostate cancer cell lines.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps RasGRP3 (B-1)

    sc-376745
    200 µg/ml
    $316.00

    RasGRP3 (B-1): m-IgG3 BP-HRP Kit

    sc-550461
    200 µg Ab; 40 µg BP
    $354.00

    RasGRP3 (B-1) peptide neutralisant

    sc-376745 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-376745 P appropriate for?

    Posée par: Germaine
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_9, d_7, h_4CST
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    Rated 5 de 5 de par Satisfactory Western blot data of RasGRP3Satisfactory Western blot data of RasGRP3 expression in non-transfected and human RasGRP3 transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2013-09-18
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    Anticorps RasGRP3 (B-1) est évalué 5.0 de 5 de 1.
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