In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S Proteasome. The 26S Proteasome is a protease complex that selectively breaks down proteins that have been modified by polyubiquitin chains. It is made up of two multisubunit complexes: the 20S Proteasome chamber, which serves as the proteolytic core of the complex and two 19S regulatory particles which recognize and unfold ubiquitinated proteins. PSMD2 (proteasome (prosome, macropain) 26S subunit, non-ATPase 2), also known as S2, TRAP2 (tumor necrosis factor type 1 receptor-associated protein 2) or p97, is a regulatory component of the 26S proteasome. It is expressed in skeletal muscle, brain, liver, placenta, kidney, pancreas, lung and heart. PSMD2 is one of the non-ATPase regulatory subunits of the 19S regulator lid and is implicated in substrate recognition and binding.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PSMD2 (C-10) | sc-271584 | 200 µg/ml | $316.00 | |||
PSMD2 (C-10): m-IgG Fc BP-HRP Kit | sc-540249 | 200 µg Ab; 10 µg BP | $354.00 | |||
PSMD2 (C-10): m-IgG1 BP-HRP Kit | sc-541998 | 200 µg Ab; 20 µg BP | $354.00 |