ACCÈS RAPIDE AUX LIENS
In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome are formed, which are responsible for proteolysis. These components of the 26S proteasome include Rpn10a through Rpn10e, or, alternatively, pUb-R2 through pUb-R5, and can be generated by a single Rpn10 gene by developmentally regulated alternative splicing. Gankyrin and p44S10 are proteasome regulatory particles that are expressed in heart, liver, skeletal muscle and pancreas. Proteasome component C2 (PROS-30), also designated Macropain subunit C2, is a prosomal protein involved in a non-lysosomal atp/ubiquitin-dependent proteolytic pathway. PSMC4 (26S protease regulatory subunit 6B) is involved in the ATP-dependent degradation of ubiquitinated proteins. PSMC4 interacts with with gankyrin, a liver oncoprotein as well as with a liver-specific member of the nuclear hormone receptor superfamily.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PSMC4 (G-5) | sc-166529 | 200 µg/ml | $316.00 | |||
PSMC4 (G-5): m-IgG Fc BP-HRP Kit | sc-540117 | 200 µg Ab; 10 µg BP | $354.00 | |||
PSMC4 (G-5): m-IgG1 BP-HRP Kit | sc-541913 | 200 µg Ab; 20 µg BP | $354.00 |