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PIS1, also known as CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase) or PIS (phosphatidylinositol synthase), is a 213 amino acid multi-pass membrane protein that belongs to the CDP-alcohol phosphatidyltransferase class-I family and exists as two alternatively spliced isoforms. Localizing to Golgi apparatus and the cytoplasmic side of endoplasmic reticulum, PIS1 is widely expressed, with highest expression in adult liver and skeletal muscle. PIS1 catalyzes the biosynthesis of phosphatidylinositol (PtdIns), as well as the PtdIns-inositol exchange reaction, which is due to the reverse reaction of PtdIns synthase and is CMP-dependent. PIS1 may also reduce excessive cellular PtdIns. Highly conserved in yeast and mammals, PIS1 is encoded by a gene that maps to human chromosome 16p11.2.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PIS1 (D-1) | sc-514565 | 200 µg/ml | $316.00 | |||
PIS1 (D-1): m-IgG Fc BP-HRP Kit | sc-538663 | 200 µg Ab; 10 µg BP | $354.00 | |||
PIS1 (D-1): m-IgGκ BP-HRP Kit | sc-536317 | 200 µg Ab; 40 µg BP | $354.00 | |||
PIS1 (D-1) peptide neutralisant | sc-514565 P | 100 µg/0.5 ml | $68.00 |