PGRMC1 (progesterone receptor membrane component 1), also known as MPR, is a 195 amino acid single-pass membrane protein that localizes to both the endoplasmic reticulum and to the microsome and contains one cytochrome b5 heme-binding domain. Expressed in a variety of tissues with highest expression in kidney and liver, PGRMC1 functions as a receptor for progesterone, a steroid hormone that is involved in embryonic development and is crucial for proper female maturation. The gene encoding PGRMC1 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PGRMC1 (C-3) | sc-271275 | 200 µg/ml | $316.00 | |||
PGRMC1 (C-3): m-IgG Fc BP-HRP Kit | sc-537601 | 200 µg Ab; 10 µg BP | $354.00 | |||
PGRMC1 (C-3): m-IgGκ BP-HRP Kit | sc-534912 | 200 µg Ab; 40 µg BP | $354.00 | |||
PGRMC1 (C-3): m-IgG1 BP-HRP Kit | sc-545254 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps PGRMC1 (C-3) X | sc-271275 X | 200 µg/0.1 ml | $316.00 |