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Pyruvate carboxylase (PCB) is a biotinylated mitchondrial enzyme that catalyzes the synthesis of oxaloacetate from pyruvate in a tissue specific manner. In addition to covalently binding the biotin cofactor, PCB contains consensus sequences for the attachment of ATP and the substrate pyruvate. The PCB gene is located on the long arm of chromosome 11. Mutations in PCB metabolism (pyruvate carboxylase deficiency) are known to cause lactic acidosis, hypoglycemia and mental retardation.
Alexa Fluor® est une marque déposée de Molecular Probes Inc., OR., USA
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PCB (F-3) | sc-365491 | 200 µg/ml | $316.00 | |||
PCB (F-3): m-IgG3 BP-HRP Kit | sc-550430 | 200 µg Ab; 40 µg BP | $354.00 | |||
PCB (F-3) peptide neutralisant | sc-365491 P | 100 µg/0.5 ml | $68.00 |