Anticorps NUDC (JT-9): sc-100794
- L'Anticorps NUDC (JT-9) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 100 µg/ml
- dirigé contre la NUDC recombinante d'origine human
- recommandé pour la détection de NUDC d'origine human par WB, IP, IF et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire NUDC (JT-9). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
NUDC (nuclear distribution gene C homolog, A. nidulans), also known as HNUDC, MNUDC or NPD011, is a ubiquitously expressed protein that is conserved from fungus to human. Highly expressed in proliferating cells, NUDC localizes to the cytoplasm and nucleus, contains a CS domain and participates in neurogenesis, mitosis, nuclear migration and cytokinesis. At the onset of mitosis, NUDC is phosphorylated by Plk. This modification of NUDC is required for proper mitotic spindle formation, chromosome separation during mitosis, cytokinesis and cell proliferation. In neurons and fibroblasts, NUDC forms a complex with LIS1 that localizes to the microtubule network and microtubule-organizing center and facilitates nuclear movement and transport in migrating neurons. In addition, the NUDC/LIS1 complex can associate with the minus-end directed Dynein/Dynactin motor complex and, together, these complexes cooperate in the regulation of cytokinesis.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NUDC (JT-9) | sc-100794 | 100 µg/ml | $333.00 |