Anticorps NR2E1 (EE-9): sc-100905
- L'Anticorps NR2E1 (EE-9) est un monoclonal de souris IgG2a κ, cité dans 1 publications, fourni en 100 µg/ml
- dirigé contre la NR2E1 recombinante d'origine human
- recommandé pour la détection de NR2E1 d'origine mouse, rat et human par WB, IP et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire NR2E1 (EE-9). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
NR2 proteins are a large family of nuclear hormone receptor transcription factors. The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding. NR2E1 (nuclear receptor subfamily 2, group E, member 1), also known as TLX, is an essential component in the formation of synaptic plasticity and dendritic structure in retinal astrocytes. In addition, NR2E1 is a orphan receptor that binds DNA as part of the hormone response element (HRE), a transcription regulator for hormones. DNA-binding orphan receptors have the conserved sequence 5'-AAGGTCA-3', a motif that determines substrate binding specificity. NR2E1 is expressed in brain tissue, with highest levels in astrocytes, and is localized to the nucleus. Mutations in the gene that encodes NR2E1 may lead to retinal dystrophy, a disorder characterized by a reduction in the thickness of the retina.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NR2E1 (EE-9) | sc-100905 | 100 µg/ml | $333.00 |