Date published: 2025-9-8

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Anticorps NOSTRIN (F-4): sc-365296

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Fiches techniques
  • L'Anticorps NOSTRIN (F-4) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 207-506 situés au niveau C-terminus de NOSTRIN d'origine human
  • recommandé pour la détection de NOSTRIN d'origine human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps NOSTRIN (F-4) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps NOSTRIN (F-4) (voir Informations pour la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    NOSTRIN (nitric oxide synthase trafficker isoform 1), also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins. NOSTRIN is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. It consists of an N-terminal Cdc15 domain with an FCH (Fes/CIP homology) region, two coiled coil domains and a C-terminal SH3 domain. NOSTRIN typically exists as a trimer. It functions as an adaptor protein binding to caveolin-1 via an internal domain and NOS3 via its SH3 domain, forming a ternary complex which facilitates caveolar transport of NOS3. The NOS3 protein is responsible for the production of nitric oxide (NO), a potent mediator in various biological processes. The translocation of NOS3 from the plasma membrane to intracellular vesicle-like structures diminishes NO production. NOSTRIN also interacts with Dynamin and N-WASP via its SH3 domain.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps NOSTRIN (F-4)

    sc-365296
    200 µg/ml
    $316.00

    NOSTRIN (F-4): m-IgGκ BP-HRP Kit

    sc-535183
    200 µg Ab; 40 µg BP
    $354.00

    NOSTRIN (F-4): m-IgG2b BP-HRP Kit

    sc-549356
    200 µg Ab; 10 µg BP
    $354.00

    Can NOSTRIN (F-4): sc-365296 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: Professor Griffin
    Thank you for your question. Yes, NOSTRIN (F-4): sc-365296 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-03-01
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    Rated 5 de 5 de par Produced beautiful immunoperoxidase cytoplasmicProduced beautiful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human skeletal muscle tissue. -SCBT QC
    Date de publication: 2015-04-25
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    Anticorps NOSTRIN (F-4) est évalué 5.0 de 5 de 2.
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