Anticorps MYL9/MYL12A/B (D-9): sc-48414
- L'Anticorps MYL9/MYL12A/B (D-9) est un monoclonal de souris IgG1 κ, cité dans 8 publications, fourni en 200 µg/ml
- soulevée à l'encontre des acides aminés 1-172 représentant l'intégralité de MRCL3 d'origine human.
- recommandé pour la détection de the myosin regulatory light chains encoded by MYL9, MYL12A and MYL12B, and the LOC391722 protein of human origin; Mylc2b, Myl9 and Myl12a of mouse origin; and Mrlcb and Myl9 of rat origin par WB, IP, IF, IHC(P) et ELISA
- Voir MYL9/MYL12A/B (E-4): sc-28329 pour d'autres anticorps conjugués MYL9/MYL12A/B, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps MYL9/MYL12A/B (D-9) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps MYL9/MYL12A/B (D-9) (voir Informations pour la commande ci-dessous).
Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of myosin have been cloned: smooth muscle myosins, striated muscle myosins and non-muscle myosins. Myosin regulatory light chains, including MYL12A (also known as MRLC3 or MLCB), MYL12B (also known as MRLC2) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps MYL9/MYL12A/B (D-9) | sc-48414 | 200 µg/ml | $316.00 | |||
MYL9/MYL12A/B (D-9): m-IgG Fc BP-HRP Kit | sc-536835 | 200 µg Ab; 10 µg BP | $354.00 | |||
MYL9/MYL12A/B (D-9): m-IgGκ BP-HRP Kit | sc-534002 | 200 µg Ab; 40 µg BP | $354.00 | |||
MYL9/MYL12A/B (D-9): m-IgG1 BP-HRP Kit | sc-544849 | 200 µg Ab; 20 µg BP | $354.00 |