Date published: 2025-9-8

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Anticorps MetAP-2 (G-5): sc-166826

5.0(2)
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Fiches techniques
  • L'Anticorps MetAP-2 (G-5) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 59-72 près de N-terminus de MetAP-2 d'origine human
  • recommandé pour la détection de MetAP-2 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • 2b BP-HRP">m-IgG2b BP-HRP est le réactif de détection secondaire préféré pour l'anticorps MetAP-2 (G-5) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps MetAP-2 (G-5)(voir les informations relatives à la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. MetAP-1 and MetAP-2 control cell proliferation in mammalian cells. MetAP-2 is highly conserved between human and Saccharomyces cerevisiae. Neurofibromin (NF1) regulates MetAp-2 and increased expression of MetAP-2 correlates with several forms of cancer. Inhibitors of MetAP-2 are potential targets in cancer therapeutics, particularly in NF1-associated tumor proliferation. Chemotherapeutic drugs such as ovalicin and fumagillin bind to the active site of and inhibit MetAp-2.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps MetAP-2 (G-5)

    sc-166826
    200 µg/ml
    $316.00

    MetAP-2 (G-5): m-IgG2b BP-HRP Kit

    sc-548531
    200 µg Ab; 10 µg BP
    $354.00

    MetAP-2 (G-5) peptide neutralisant

    sc-166826 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-166826 P appropriate for?

    Posée par: TinTin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-03-01
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    Rated 5 de 5 de par Produced positive Western Blot data of MetAPProduced positive Western Blot data of MetAP-2 expression in non-transfected and human MetAP-2 transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2015-02-01
    Rated 5 de 5 de par Nice Western Blot data of MetAPNice Western Blot data of MetAP-2 expression in non-transfected and mouse MetAP-2 transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2014-01-08
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    Anticorps MetAP-2 (G-5) est évalué 5.0 de 5 de 2.
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