Anticorps H2-I/Ab (DaB2): sc-65383
- L'anticorps H2-I/Ab DaB2 est un monoclonal IgG1 de souris fourni en 100 µg/ml
- élevé contre les splénocytes C57B1 d'origine mouse.
- recommandé pour la détection de MHC class II I-Ab haplotype d'origine mouse par IF et FCM
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire H2-I/Ab (DaB2). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
Major histocompatibility complex (MHC) molecules form an integral part of the immune response system. They are cell-surface receptors that bind foreign peptides and present them to cytotoxic T lymphocytes (CTLs). MHC class I molecules consist of two polypeptide chains, an a or heavy chain and a non-covalently associated protein, β-2-Microglobulin. MHC class II molecules consist of a non-covalent complex of an α and β chain and are involved in antigen presentation by antigen presenting cells (APCs) to CD4+ T cells. They are expressed on APCs including B cells, macrophages, monocytes and dendritic cells, and are inducible by interferon-γ on a number of other cells, such as endothelium and epithelial cells. The mouse H2-Ab locus is orthologous to human DQB, which varies from typical class II genes in that both the a and b chains are polymorphic. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps H2-I/Ab (DaB2) | sc-65383 | 100 µg/ml | $316.00 |