Anticorps GSTO1/2 (D-12): sc-166040
- L'Anticorps GSTO1/2 (D-12) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- soulevée contre les acides aminés 1-241 représentant l'intégralité de la GSTO1 d'origine human.
- recommandé pour la détection de GSTO1, GSTO2 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- m-IgG Fc BP-HRP et m-IgG2a BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps GSTO1/2 (D-12) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps GSTO1/2 (D-12) (voir Informations pour la commande ci-dessous).
GSTO1 (glutathione S-transferase omega 1), also known as p28 or GSTTLp28, is a 241 amino acid protein that localizes to the cytoplasm and contains both an N-terminal and a C-terminal GST domain. Expressed ubiquitously with highest expression in heart, liver and skeletal muscle, GSTO1 exists as a homodimer that functions as both a glutathione-dependent thiol transferase and a dehydroascorbate reductase. Specifically, GSTO1 catalyzes the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens. Polymorphisms in the gene encoding GSTO1 may be associated with the development of childhood acute lymphoblastic leukemia, Parkinson's disease and Alzheimer disease. GSTO2 (glutathione S-transferase omega-2) is related to GSTO1 and is expressed in a variety of tissues throughout the body where it functions to catalyze the conversion of RX and glutathione to HX and R-S-glutathione.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GSTO1/2 (D-12) | sc-166040 | 200 µg/ml | $316.00 | |||
GSTO1/2 (D-12): m-IgG Fc BP-HRP Kit | sc-539994 | 200 µg Ab; 10 µg BP | $354.00 | |||
GSTO1/2 (D-12): m-IgG2a BP-HRP Kit | sc-546832 | 200 µg Ab; 10 µg BP | $354.00 |