frizzled Antibody (1C11): sc-13559
- frizzled Antibody (1C11) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 1-252 of frizzled of Drosophila melanogaster origin
- frizzled Antibody (1C11) is recommended for detection of frizzled of d origin by WB and IF
- Anti-frizzled Antibody (1C11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for frizzled Antibody (1C11) for WB applications. This reagent is now offered in a bundle with frizzled Antibody (1C11) (see ordering information below).
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SEE ALSO...
Frizzled Antibody (1C11) is a mouse monoclonal IgG1 kappa light chain antibody that detects frizzled protein of Drosophila origin by western blotting (WB) and immunofluorescence (IF). Anti-frizzled antibody (1C11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Frizzled protein plays a crucial role in the Wnt signaling pathway, which regulates cell proliferation, differentiation, and tissue polarity during development. This signaling pathway is vital for proper embryonic development and adult tissue homeostasis, influencing cell fate determination and stem cell maintenance. In Drosophila, frizzled is particularly important for establishing cell orientation within developing tissue, ensuring structures such as hairs and bristles align correctly. Frizzled′s ability to mediate these processes highlights significant implications in developmental biology and diseases related to cell signaling dysregulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
frizzled Antibody (1C11) References:
- The genome sequence of Drosophila melanogaster. | Adams, MD., et al. 2000. Science. 287: 2185-95. PMID: 10731132
- An estimate of the sequencing error frequency in the DNA sequence databases. | Kristensen, T., et al. 1992. DNA Seq. 2: 343-6. PMID: 1446073
- Evidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless. | Chen, CM., et al. 2004. Proc Natl Acad Sci U S A. 101: 15961-6. PMID: 15514021
- Trimeric G protein-dependent frizzled signaling in Drosophila. | Katanaev, VL., et al. 2005. Cell. 120: 111-22. PMID: 15652486
- The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye. | Djiane, A., et al. 2005. Cell. 121: 621-631. PMID: 15907474
- Molecular structure of frizzled, a Drosophila tissue polarity gene. | Adler, PN., et al. 1990. Genetics. 126: 401-16. PMID: 2174014
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
frizzled Antibody (1C11) | sc-13559 | 200 µg/ml | $322.00 | |||
frizzled Antibody (1C11): m-IgG Fc BP-HRP Bundle | sc-525479 | 200 µg Ab; 10 µg BP | $361.00 | |||
frizzled Antibody (1C11) AC | sc-13559 AC | 500 µg/ml, 25% agarose | $424.00 | |||
frizzled Antibody (1C11) HRP | sc-13559 HRP | 200 µg/ml | $322.00 | |||
frizzled Antibody (1C11) FITC | sc-13559 FITC | 200 µg/ml | $336.00 | |||
frizzled Antibody (1C11) PE | sc-13559 PE | 200 µg/ml | $349.00 | |||
frizzled Antibody (1C11) Alexa Fluor® 488 | sc-13559 AF488 | 200 µg/ml | $364.00 | |||
frizzled Antibody (1C11) Alexa Fluor® 546 | sc-13559 AF546 | 200 µg/ml | $364.00 | |||
frizzled Antibody (1C11) Alexa Fluor® 594 | sc-13559 AF594 | 200 µg/ml | $364.00 | |||
frizzled Antibody (1C11) Alexa Fluor® 647 | sc-13559 AF647 | 200 µg/ml | $364.00 | |||
frizzled Antibody (1C11) Alexa Fluor® 680 | sc-13559 AF680 | 200 µg/ml | $364.00 | |||
frizzled Antibody (1C11) Alexa Fluor® 790 | sc-13559 AF790 | 200 µg/ml | $364.00 |