Anticorps FAF1 (92-B): sc-101255
- L'Anticorps FAF1 (92-B) est un monoclonal de souris mouse IgG1 κ (chaîne légère kappa) fourni en 100 µg/ml
- dirigé contre la FAF1 recombinante d'origine human
- recommandé pour la détection de FAF1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire FAF1 (92-B). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved "death domain" and belonging to the TNF receptor superfamily. TRADD, FADD and RIP are FAS/TNF-RI interacting proteins that contain a death domain homologous region (DDH). TRADD (TNF-RI-associated death domain) and FADD (FAS-associated death domain) associate with the death domains of both FAS and TNF-RI via their DDH regions, while RIP associates exclusively with FAS. An additional FAS interacting protein designated FAF1, for FAS-associated protein factor-1, binds with the cytoplasmic tail of wild type but not lpr mutant FAS. When overexpressed in cells, FAF1 enhances the efficiency of FAS-mediated apoptosis. In contrast to TRADD, FADD and RIP, FAF1 lacks a DDH and cannot induce apoptosis independently of FAS activation.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps FAF1 (92-B) | sc-101255 | 100 µg/ml | $333.00 |