Lectin mannose-binding 1, also designated vesicular integral-membrane protein (VIP36) and lectin mannose-binding 2, also designated ER-Golgi intermediate compartment (ERGIC-53) comprise a family of membrane bound, ubiquitous proteins involved in the selective transport of newly synthesized glycoproteins from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment (ERGIC). VIP36 acts as an intracellular lectin in the early secretory pathway. It is involved in the sorting and transport of glycoproteins carrying high mannose-type glycans. ERGIC-53, a mannose-specific lectin, recognizes sugar residues of glycoproteins and glycolipids. It mediates the sorting and recycling of proteins and/or lipids. Null expression of ERGIC-53, also designated LMAN1, results in a rare autosomal recessive bleeding disorder that causes combined deficiency of both coagulation factors V and VIII.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ERGIC-53 (B-9) | sc-271517 | 200 µg/ml | $316.00 | |||
ERGIC-53 (B-9): m-IgG Fc BP-HRP Kit | sc-537651 | 200 µg Ab; 10 µg BP | $354.00 | |||
ERGIC-53 (B-9): m-IgGκ BP-HRP Kit | sc-534985 | 200 µg Ab; 40 µg BP | $354.00 | |||
ERGIC-53 (B-9): m-IgG2a BP-HRP Kit | sc-548077 | 200 µg Ab; 10 µg BP | $354.00 |