Anticorps ARHGAP1 (A-9): sc-398889
- L'Anticorps ARHGAP1 (A-9) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 1-76 situés au niveau N-terminus de ARHGAP1 d'origine human
- recommandé pour la détection de ARHGAP1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps ARHGAP1 (A-9) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps ARHGAP1 (A-9)(voir les informations de commande ci-dessous).
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. ARHGAP1 (Rho GTPase activating protein 1), also known as CDC42GAP or RhoGAP1, is a 439 amino acid protein that localizes to the cytoplasm and contains one Rho-GAP domain and one CRAL-TRIO domain. Expressed ubiquitously, ARHGAP1 exists in a complex with several other proteins, including eIF4AI and Exportin 7, and functions as a GTPase activator for Rho, Rac and Cdc42 proteins, effectively converting them to an inactive GDP-bound state. The gene encoding ARHGAP1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ARHGAP1 (A-9) | sc-398889 | 200 µg/ml | $316.00 | |||
ARHGAP1 (A-9): m-IgG Fc BP-HRP Kit | sc-538538 | 200 µg Ab; 10 µg BP | $354.00 | |||
ARHGAP1 (A-9): m-IgGκ BP-HRP Kit | sc-536169 | 200 µg Ab; 40 µg BP | $354.00 | |||
ARHGAP1 (A-9): m-IgG1 BP-HRP Kit | sc-545754 | 200 µg Ab; 20 µg BP | $354.00 |