Anticorps AKR7A (E-11): sc-365400
- L'Anticorps AKR7A (E-11) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 335-359 au niveau C-terminus de AKR7A2 d'origine human
- recommandé pour la détection de AKR7A2, AKR7A3 and AKR7A4 of human origin, AKR7A5 of mouse origin and AKR7A2 of rat origin par WB, IP, IF, IHC(P) et ELISA
- 1 BP-HRP">m-IgG1 BP-HRP est le réactif de détection secondaire préféré pour l'anticorps AKR7A (E-11) pour les applications WB et IHC(P). Ce réactif est désormais proposé en association avec l'anticorps AKR7A (E-11)(voir les informations relatives à la commande ci-dessous).
The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of Aflatoxin B1 and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p36.13, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate Aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent. AKR7A3 is believed to be a homodimer expressed in kidney, colon, pancreas, endometrium and adenocarcinoma.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps AKR7A (E-11) | sc-365400 | 200 µg/ml | $316.00 | |||
AKR7A (E-11): m-IgG1 BP-HRP Kit | sc-552009 | 200 µg Ab; 20 µg BP | $354.00 | |||
AKR7A (E-11) peptide neutralisant | sc-365400 P | 100 µg/0.5 ml | $68.00 |