Troponin I-FS Antibody (C-11): sc-377451
- Troponin I-FS Antibody (C-11) is a mouse monoclonal IgG1 κ Troponin I-FS antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 143-179 near the C-terminus of Troponin I-FS of human origin
- Troponin I-FS Antibody (C-11) is recommended for detection of Troponin I-FS of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-Troponin I-FS Antibody (C-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Troponin I-FS Antibody (C-11) for WB and IHC(P) applications. This reagent is now offered in a bundle with Troponin I-FS Antibody (C-11) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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SEE ALSO...
Troponin I-FS Antibody (C-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects Troponin I-FS protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Troponin I-FS antibody (C-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Troponin I-FS plays a critical role in muscle contraction by regulating the interaction between actin and myosin, which are essential for muscle fiber contraction and relaxation. Troponin I-FS is part of the troponin complex, which also includes Troponin C and Troponin T, and is specifically involved in the calcium-mediated signaling pathway that triggers muscle contraction. Troponin I-FS in the troponin complex allows for precise control of muscle contraction in response to calcium levels, making this protein vital for proper cardiac and skeletal muscle function. Abnormalities in Troponin I-FS expression or function can lead to various muscle disorders, highlighting Troponin I-FS importance in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Troponin I-FS Antibody (C-11) References:
- Structure and expression of the murine slow/cardiac troponin C gene. | Parmacek, MS. and Leiden, JM. 1989. J Biol Chem. 264: 13217-25. PMID: 2753913
- cDNA clone and expression analysis of rodent fast and slow skeletal muscle troponin I mRNAs. | Koppe, RI., et al. 1989. J Biol Chem. 264: 14327-33. PMID: 2760067
- A direct regulatory role for troponin T and a dual role for troponin C in the Ca2+ regulation of muscle contraction. | Potter, JD., et al. 1995. J Biol Chem. 270: 2557-62. PMID: 7852318
- Structure and regulation of the mouse cardiac troponin I gene. | Ausoni, S., et al. 1994. J Biol Chem. 269: 339-46. PMID: 8276817
- Actin cytoskeleton. Setting the pace of cell movement. | Barkalow, K. and Hartwig, JH. 1995. Curr Biol. 5: 1000-2. PMID: 8542272
- Myosins: matching functions with motors. | Baker, JP. and Titus, MA. 1998. Curr Opin Cell Biol. 10: 80-6. PMID: 9484598
- A new look at thin filament regulation in vertebrate skeletal muscle. | Squire, JM. and Morris, EP. 1998. FASEB J. 12: 761-71. PMID: 9657517
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin I-FS Antibody (C-11) | sc-377451 | 200 µg/ml | $322.00 | |||
Troponin I-FS Antibody (C-11): m-IgGκ BP-HRP Bundle | sc-523331 | 200 µg Ab, 40 µg BP | $361.00 | |||
Troponin I-FS Antibody (C-11) AC | sc-377451 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Troponin I-FS Antibody (C-11) HRP | sc-377451 HRP | 200 µg/ml | $322.00 | |||
Troponin I-FS Antibody (C-11) FITC | sc-377451 FITC | 200 µg/ml | $336.00 | |||
Troponin I-FS Antibody (C-11) PE | sc-377451 PE | 200 µg/ml | $349.00 | |||
Troponin I-FS Antibody (C-11) Alexa Fluor® 488 | sc-377451 AF488 | 200 µg/ml | $364.00 | |||
Troponin I-FS Antibody (C-11) Alexa Fluor® 546 | sc-377451 AF546 | 200 µg/ml | $364.00 | |||
Troponin I-FS Antibody (C-11) Alexa Fluor® 594 | sc-377451 AF594 | 200 µg/ml | $364.00 | |||
Troponin I-FS Antibody (C-11) Alexa Fluor® 647 | sc-377451 AF647 | 200 µg/ml | $364.00 | |||
Troponin I-FS Antibody (C-11) Alexa Fluor® 680 | sc-377451 AF680 | 200 µg/ml | $364.00 | |||
Troponin I-FS Antibody (C-11) Alexa Fluor® 790 | sc-377451 AF790 | 200 µg/ml | $364.00 | |||
Troponin I-FS (C-11) Neutralizing Peptide | sc-377451 P | 100 µg/0.5 ml | $69.00 |