(S)-CPW 399 is a subtype-selective weakly desensitising AMPA agonist. At GluR1 and GluR2 subunit-containing AMPA receptors, exhibits potent agonist activity. Excitotoxic in vitro. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4.
1. Campiani, G., et al. 2001. J. Med. Chem. 44: 4501-4504. 2. Sinclair, C., et al. 2003. Neurochem.Int. 42: 499-510. 3. Butini, S., et al. 2008. J. Med. Chem. 51: 6614-6618.
Estado de Materia
Soluble to 50 mM in Water
Store at -20° C
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
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