MDMA Antibody (3G8): sc-57908

MDMA Antibody (3G8) is a mouse monoclonal IgG1 kappa light chain antibody that detects MDMA protein of non-species reactive by enzyme-linked immunosorbent assay (ELISA). Anti-MDMA antibody (3G8) is available as the non-conjugated isotype antibody. MDMA, or 3,4-methylenedioxy-N-methylamphetamine, is widely recognized by its street name ecstasy and is a semisynthetic entactogen belonging to the phenethylamine family. This compound plays a significant role in modulating neurotransmitter systems in the brain, particularly by stimulating the release of serotonin while inhibiting the reuptake of serotonin, dopamine, and norepinephrine. MDMA′s function lies in inducing feelings of empathy, energy, and euphoria, which can be beneficial in therapeutic contexts, especially in treating conditions like PTSD. MDMA reaches peak blood concentrations within 1.5 to 3 hours post-ingestion and metabolizes gradually, with levels halving approximately every 8 hours. MDMA has been shown to promote the release of various hormones, including prolactin and vasopressin, which can have additional physiological effects. With a molecular weight of 193.25 g/mol, MDMA is a chiral compound typically administered as a racemate, making MDMA a subject of interest in both clinical and research settings.

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MDMA Antibody (3G8) References:

1. The pharmacology and toxicology of 'ecstasy' (MDMA) and related drugs.  |  Kalant, H. 2001. CMAJ. 165: 917-28. PMID: 11599334
2. Imaging brain activity in conscious monkeys following oral MDMA ('ecstasy').  |  Brevard, ME., et al. 2006. Magn Reson Imaging. 24: 707-14. PMID: 16824965
3. Characteristics and trends of 3,4-methylenedioxymethamphetamine (MDMA) tablets found in Taiwan from 2002 to February 2005.  |  Teng, SF., et al. 2006. Forensic Sci Int. 161: 202-8. PMID: 16842946
4. Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice.  |  Risbrough, VB., et al. 2006. Neuropsychopharmacology. 31: 2349-58. PMID: 16855533
5. Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine.  |  Pirnay, SO., et al. 2006. Clin Chem. 52: 1728-34. PMID: 16858076
6. Context-dependent behavioural and neuronal sensitization in striatum to MDMA (ecstasy) administration in rats.  |  Ball, KT., et al. 2006. Eur J Neurosci. 24: 217-28. PMID: 16882018
7. Repeated weekly exposure to MDMA, methamphetamine or their combination: long-term behavioural and neurochemical effects in rats.  |  Clemens, KJ., et al. 2007. Drug Alcohol Depend. 86: 183-90. PMID: 16884865
8. Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: involvement of nicotinic receptors.  |  Chipana, C., et al. 2006. Neuropharmacology. 51: 885-95. PMID: 16901518

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MDMA Antibody (3G8) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MDMA Antibody (3G8) Specifications

Alternate Product Name: MDMA

Product Clone Name: 3G8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: MDMA

Epitope Species: bovine

Product Reactivity/Detection: MDMA

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for MDMA Antibody (3G8): N/A