KIF2A Antibody (F-2): sc-271027

KIF2A Antibody (F-2) is a mouse monoclonal IgG2a antibody that detects KIF2A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KIF2A, a member of the kinesin superfamily, plays a crucial role in axonal transport and is essential for proper development and function of neurons. This motor protein is primarily located in developing axons, where KIF2A facilitates transport of vital cellular components, including organelles and macromolecules, along microtubules. The effective transport of these materials is critical for neuronal growth and connectivity, as such movement ensures developing neurons receive necessary resources to establish synaptic connections and maintain cellular health. Additionally, KIF2A is regulated by various factors, including the synthetic retinoid N-(4-hydroxyphenyl)-all-trans-retinamide, which has been shown to induce apoptotic cell death in vitro, highlighting KIF2A′s importance in both normal cellular processes and potential therapeutic contexts. Anti-KIF2A antibody (F-2) serves as an invaluable tool for researchers studying neuronal development and underlying mechanisms of neurodegenerative diseases.

The preferred KIF2A antibody is KIF2A Antibody (D-7): sc-271471.