Molecular structure of Isoapoptolidin, CAS Number: 476647-30-0
Isoapoptolidin (CAS 476647-30-0)
Application:
Isoapoptolidin is a ring expanded isomer of apoptolidin
CAS Number:
476647-30-0
Purity:
>90%
Molecular Weight:
1129.4
Molecular Formula:
C58H96O21
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Isopoptolidin, originally isolated from a Nocardiopsis sp., is a ring expanded isomer of apoptolidin. In water, an equilibrium mixture of apoptolidin:isoapoptolidin (~1.5:1) is formed within hours. In a rapid F0F1-ATPase assay, isoapoptolidin exhibited an IC50 of 17 μM compared to 0.7 μM for apoptolidin.
Isoapoptolidin (CAS 476647-30-0) References
- Isoapoptolidin: structure and activity of the ring-expanded isomer of apoptolidin. | Wender, PA., et al. 2002. Org Lett. 4: 3819-22. PMID: 12599467
- Toward a stable apoptolidin derivative: identification of isoapoptolidin and selective deglycosylation of apoptolidin. | Pennington, JD., et al. 2002. Org Lett. 4: 3823-5. PMID: 12599468
- Isolation, structure determination, and anti-cancer activity of apoptolidin D. | Wender, PA. and Longcore, KE. 2007. Org Lett. 9: 691-4. PMID: 17286376
Inhibitor of:
ATP5, and ATPase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Isoapoptolidin, 100 µg | sc-202187 | 100 µg | $350.00 |