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Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US, Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxesShips via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal health products, bulky and/or heavy items
hnRNP A1 Antibody (4B10) is a high quality monoclonal hnRNP A1 antibody (also designated HNRNPA1 antibody) suitable for the detection of the hnRNP A1 protein of mouse, rat and human origin. hnRNP A1 Antibody (4B10) is available as both the non-conjugated anti-hnRNP A1 antibody form, as well as multiple conjugated forms of anti-hnRNP A1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. The A/B subfamily of hnRNPs include A1, A2/B1, A3 and A0, and in Xenopus, hnRNP A1, A2 and A3 are ubiquitously expressed throughout development as well as in adult tissues. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing fac ors and by influencing the splice site selection on pre-mRNA. The hnRNP A0 gene is distinct from the other A/B family members, and it encodes a low-abundance protein, which is implicated in mRNA stability.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Especies | Nombre del Gen | Gen ID | Ubicación en el cromosoma | Numero de Acceso de Isoforma (ARNm) | Número de Acceso de la Proteína | Número OMIM™ |
---|---|---|---|---|---|---|
Human | HNRNPA1 | 3178 | 12q13.13 | XM_005268826, XM_017019251, NM_002136, NM_031157 | P09651 | 164017 |
Mouse | Hnrnpa1 | 15382 | 15 F3 | NM_001039129, NM_010447 | P49312 | N/A |