Anti-GNMT Anticuerpo A-4 es un monoclonal de ratón IgG1 κ GNMT Anticuerpo, ver las 4 publicaciones, proporcionado como 200 µg/ml
raised against amino acids 71-295 mapping at the C-terminus of GNMT of human origin
GNMT Anticuerpo (A-4) es recomendado para detectar glycine N-methyltransferase de human origen, mediante WB, IP, IF, IHC(P) y ELISA
GNMT Anticuerpo (A-4) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de GNMT (A-4): sc-166834.
m-IgGκ BP-HRP is the preferred secondary detection reagent for GNMT Antibody (A-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with GNMT Antibody (A-4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
GNMT Antibody (A-4) is a high quality monoclonal GNMT antibody (also designated GNMT antibody) suitable for the detection of the GNMT protein of human origin. GNMT Antibody (A-4) is available as both the non-conjugated anti-GNMT antibody form, as well as multiple conjugated forms of anti-GNMT antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Glycine N-methyltransferase (GNMT) is a 295 amino acid protein that catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). This process indicates that GNMT probably plays a crucial role in the regulation of tissue concentration of AdoMet and in the metabolism of methionine. Originally identified as a methyl donor, AdoMet is now considered a key metabolite that regulates hepatocyte growth, death and differentiation. Biosynthesis of AdoMet occurs in all mammalian cells as the first step in methionine catabolism in a reaction catalyzed by methionine adenosyltransferase (MAT). Decreased hepatic AdoMet biosynthesis is a consequence of all forms of chronic liver injury. In chronic liver AdoMet deficiency, the liver is predisposed to further injury and can develop spontaneous steatohepatitis and hepatocellular carcinoma. However, impaired AdoMet metabolism, which occurs in patients with mutations of GNMT, can also lead to liver injury.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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To place an order using RMB or to ship to mainland China, please visit www.scbio.cn