Glucagon Antibody (4j80): sc-71152

Glucagon Antibody (4j80) is a mouse monoclonal IgG1 antibody that detects glucagon in mouse, rat, human, porcine, feline, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Glucagon plays a crucial role in glucose metabolism as a counter-regulatory hormone to insulin, promoting the conversion of glycogen to glucose in the liver, which is vital for maintaining blood sugar levels, especially during fasting or low-energy states. The importance of glucagon extends beyond glucose homeostasis; this hormone also influences various physiological processes, including the regulation of appetite and energy expenditure. Additionally, glucagon is part of a larger family of hormones that includes Glucagon-like peptide-1 (GLP-1) and Glucagon-like peptide-2 (GLP-2), which have distinct roles in the central nervous system and gastrointestinal tract, respectively. The interactions of glucagon with its receptors and other signaling pathways underscore its significance in metabolic regulation and highlight the potential for therapeutic interventions targeting glucagon signaling in metabolic disorders. Anti-glucagon antibody (4j80) serves as an essential tool for researchers studying these complex biological processes and their implications in health and disease.

The preferred Glucagon antibody is Glucagon Antibody (K79bB10): sc-57171.