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EMMPRIN/CD147 Antibody (F-5) - Western Blotting - Image 303845
EMMPRIN 抗体 (F-5): sc-374101. WI-38 (A), A-431 (B) 和 HeLa (C) 全细胞裂解液中 EMMPRIN 表达的 Western 印迹分析.
EMMPRIN 抗体 (F-5): sc-374101. WI-38 (A), A-431 (B) 和 HeLa (C) 全细胞裂解液中 EMMPRIN 表达的 Western 印迹分析.

EMMPRIN/CD147 抗体 (F-5): sc-374101

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说明书
  • EMMPRIN/CD147抗体(F-5)是小鼠单克隆IgG1 κ, 在9篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于human物种的EMMPRIN的N-terminus附近的氨基酸13-51之间
  • 推荐用于 mouse, rat 和 human 来源的EMMPRIN WB, IP, IF 和 ELISA检测; 也和以下物种反应，包括： bovine
  • 看 EMMPRIN/CD147 (B-5): sc-46700，可查看有标记的 EMMPRIN/CD147 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是EMMPRIN/CD147 Antibody (F-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与EMMPRIN/CD147 Antibody (F-5) 打包提供（请参阅下面的订购信息）。
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関連項目

细胞外基质金属蛋白酶诱导因子（EMMPRIN），也称为basigin或CD147，参与调节表皮-真皮界面处的基质重塑。EMMPRIN刺激成纤维细胞产生间质胶原酶、明胶酶A、基质分解素-1和各种金属蛋白酶（MMP）。这些酶通常在组织降解和伤口愈合过程中增加，是癌症侵袭和转移的重要因素。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

EMMPRIN/CD147 抗体 (F-5) 参考文献:

  1. EMMPRIN激活心肌细胞中的多种转录因子，并通过Rac1依赖的PI3K/Akt/IKK/NF-kappaB和MKK7/JNK/AP-1信号传导诱导白细胞介素-18的表达。  |  Venkatesan, B., et al. 2010. J Mol Cell Cardiol. 49: 655-63. PMID: 20538003
  2. EMMPRIN：一种新型调节因子，可调节多发性硬化症和实验性自身免疫性脑脊髓炎中白细胞向中枢神经系统的迁移。  |  Agrawal, SM., et al. 2011. J Neurosci. 31: 669-77. PMID: 21228176
  3. EMMPRIN及其配体亲环蛋白A作为炎症性心肌病的新型诊断标志物。  |  Seizer, P., et al. 2013. Int J Cardiol. 163: 299-304. PMID: 21724278
  4. EMMPRIN通过MMP介导的occludin裂解调节上皮屏障功能：对干眼病的影响。  |  Huet, E., et al. 2011. Am J Pathol. 179: 1278-86. PMID: 21777561
  5. 肿瘤细胞与巨噬细胞的相互作用通过分泌 EMMPRIN 增加了血管生成。  |  Amit-Cohen, BC., et al. 2013. Front Physiol. 4: 178. PMID: 23874303
  6. 小鼠牙齿发育过程中caveolin-1和EMMPRIN的时空表达。  |  Shi, L., et al. 2016. J Mol Histol. 47: 337-44. PMID: 27075451
  7. 上皮牙源性病变中MMP-13和EMMPRIN的免疫组织化学分析。  |  de Andrade Santos, PP., et al. 2019. Eur Arch Otorhinolaryngol. 276: 3203-3211. PMID: 31440816
  8. 小檗碱调控 miR150-5p 抑制氧化LDL 诱导的巨噬细胞中 P2X7 受体、EMMPRIN 和 MMP-9 的表达  |  Lu, L., et al. 2021. Front Pharmacol. 12: 639558. PMID: 33959010
  9. 托珠单抗（TCZ）通过调节miR-146a-5p和EMMPRIN/CD147，减少类风湿性关节炎中的血管生成。  |  Zisman, D., et al. 2021. Front Immunol. 12: 739592. PMID: 34975837
  10. 细胞外小泡以一种依赖于 EMMPRIN 和 MMP-2 的方式促进髓母细胞瘤的转移  |  Jackson, HK., et al. 2023. Cancers (Basel). 15: PMID: 37174066

订购信息

产品名称产品编号规格价格数量收藏夹

EMMPRIN/CD147 抗体 (F-5)

sc-374101
200 µg/ml
$322.00

EMMPRIN/CD147 (F-5): m-IgG Fc BP-HRP 套装

sc-537914
200 µg Ab; 10 µg BP
$361.00

EMMPRIN/CD147 (F-5): m-IgGκ BP-HRP 套装

sc-535384
200 µg Ab; 40 µg BP
$361.00

EMMPRIN/CD147 (F-5): m-IgG1 BP-HRP 套装

sc-545441
200 µg Ab; 20 µg BP
$361.00

EMMPRIN/CD147 (F-5) 中和勝肽

sc-374101 P
100 µg/0.5 ml
$69.00

Can this blocking peptide（sc-374101 P） be used in animal experiments （tail vein injection in mice）?

Asked by: feige
Thank you for your question. The blocking peptide is intended to be used as a negative control for the antibody. It can be pre-incubated with the corresponding antibody and used to block the antigen binding sites of the specific antibody, prior to dilution in your research application. We do not recommend using the blocking peptide for tail injections in mice.
Answered by: Technical Support
Date published: 2018-12-05

What application is the blocking peptide sc-374101 P appropriate for?

Asked by: DefinitelyNotMatt
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by Vihra from Accurate shipmentGreat! The antibody arrived in a week time. Our client was happy with such delivery.
Date published: 2022-07-04
Rated 5 out of 5 by JT from Very robustVery robust, positive signal obtained in WB in SK-MEL-28 whole cell lysate. -SCBT QC
Date published: 2015-04-05
Rated 5 out of 5 by SH from Worked well in WB in WIWorked well in WB in WI-38, A-431 and HeLa whole cell lysates. -SCBT QC
Date published: 2015-01-24
Rated 5 out of 5 by MC from Great immunofluorescence cytoplasmic stainingGreat immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-01-11
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EMMPRIN/CD147 抗体 (F-5) is rated 5.0 out of 5 by 4.
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