Anti-DSCR 1 Anticuerpo G-2 es un monoclonal de ratón IgG1 κ DSCR 1 Anticuerpo, ver las 9 publicaciones, proporcionado como 200 µg/ml
producido contra los amino ácidos 1-197 de la proteina total DSCR 1 de origen human
DSCR 1 Anticuerpo (G-2) es recomendado para detectar DSCR 1 de mouse, rat y human origen, mediante WB, IP, IF y ELISA
DSCR 1 Anticuerpo (G-2) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de DSCR 1 (G-2): sc-377507.
m-IgGκ BP-HRP is the preferred secondary detection reagent for DSCR 1 Antibody (G-2) for WB applications. This reagent is now offered in a bundle with DSCR 1 Antibody (G-2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
DSCR 1 Antibody (G-2) is a high quality monoclonal DSCR 1 antibody (also designated DSCR 1 antibody) suitable for the detection of the DSCR 1 protein of mouse, rat and human origin. DSCR 1 Antibody (G-2) is available as both the non-conjugated anti-DSCR 1 antibody form, as well as multiple conjugated forms of anti-DSCR 1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. DSCR1 (Down syndrome critical region 1), also known as Calcipressin-1, Adapt78, MCIP1 (myocyte-enriched calcineurin-interacting protein 1) or regulator of calcineurin 1, is a 252 amino acid protein that belongs to the RCAN family and exists as four alternatively spliced isoforms. Abundantly expressed in skeletal muscle, brain and heart, DSCR 1 is thought to influence cardiac and nervous system development. Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome. DSCR1 interacts with Raf-1 and has been observed to inhibit calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. The gene encoding DSCR 1 maps to human chromosome 21, which which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer′s disease, amyotrophic lateral sclerosis and, most notably, Down syndrome (also known as trisomy 21).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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