Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and maintain the overall structural integrity of epithelial cells. Cytokeratins are useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin polypeptides are designated 1 to 20 and are divided into the type I and type II subgroups. The type II family members comprise the basic to neutral cytokeratins 1-8, while the type I group comprises the acidic cytokeratins 9-20. Cytokeratin 5 is expressed in normal basal cells. Mutations of the cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB). Cytokeratin 6 is expressed in suprabasal keratinocytes of wounded epidermis and in acrosyringeal keratinocytes in normal skin. Cytokeratin 18 is one of the first keratins expressed in the embryo, and persists into adult tissues. It is a major component of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.