C/EBP beta Antibody (47A1): sc-56637
- C/EBP beta Antibody (47A1) is a mouse monoclonal IgG1, cited in 11 publications, provided at 50 µg/0.5 ml
- raised against amino acids 1-271 of C/EBP β of human origin
- recommended for detection of C/EBP β of mouse, rat and human origin by WB and IP
- See C/EBP beta (H-7): sc-7962 for C/EBP beta antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for C/EBP beta Antibody (47A1). This work is in progress.
C/EBP β Antibody (47A1) is a mouse monoclonal IgG1 antibody that detects C/EBP β in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). C/EBP β is a crucial transcription factor belonging to the CCAAT-enhancer binding protein family, playing a significant role in the differentiation of various cell types, including liver, adipose tissue, blood cells, and the endocrine pancreas. C/EBP β is particularly important due to its involvement in the regulation of the acute phase response in hepatocytes, a critical process for the body′s response to inflammation and injury. C/EBP β exists in multiple isoforms, generated through alternative translational initiation at several AUG start sites, which allows for a diverse range of functional activities. The phosphorylation of C/EBP β is essential for DNA binding capability, and interaction with Stat3 is vital for the interleukin 6-mediated transcription of the C/EBP β gene, linking C/EBP β directly to the acute phase response in liver cells. The upregulation and structural modification of C/EBP β isoforms during acute-phase reactions enhance binding affinity, underscoring C/EBP β′s dynamic role in cellular responses to stress and inflammation. Anti-C/EBP β antibody (47A1) is an invaluable tool for researchers studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C/EBP beta Antibody (47A1) | sc-56637 | 50 µg/0.5 ml | $322.00 |