Tra-2β Antibody (D-4): sc-166769
- Tra-2β Antibody (D-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 19-36 near the N-terminus of Tra-2β of human origin
- recommended for detection of Tra-2β of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-166769 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Tra-2β Antibody (D-4) for WB applications. These reagents are now offered in bundles with Tra-2β Antibody (D-4) (see ordering information below).
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Tra-2β Antibody (D-4) is a mouse monoclonal IgG1 antibody that detects Tra-2β in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Tra-2β is a crucial nuclear protein that plays a significant role in the regulation of pre-mRNA splicing, particularly in the formation of Tra-2/SR complexes with serine/arginine-rich splicing factors. This interaction is vital for the modulation of tissue-specific alternative splicing patterns, which are essential for proper gene expression in various biological processes. Tra-2β selectively binds to purine-rich sequences through RNP-type RNA-binding domain, facilitating mRNA splicing and influencing gene expression and cellular function. Notably, Tra-2β expression increases during the reoxygenation of hypoxic astrocytes, highlighting a potential role in cellular stress responses and neurobiology. With versatile applications and critical function in splicing regulation, anti-Tra-2β antibody (D-4) serves as an invaluable tool for researchers investigating gene expression and alternative splicing mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tra-2β Antibody (D-4) | sc-166769 | 200 µg/ml | $322.00 | |||
Tra-2β Antibody (D-4): m-IgG Fc BP-HRP Bundle | sc-540156 | 200 µg Ab; 10 µg BP | $361.00 | |||
Tra-2β Antibody (D-4): m-IgG1 BP-HRP Bundle | sc-541937 | 200 µg Ab; 20 µg BP | $361.00 | |||
Tra-2β (D-4) Neutralizing Peptide | sc-166769 P | 100 µg/0.5 ml | $69.00 | |||
Tra-2β Antibody (D-4) X | sc-166769 X | 200 µg/0.1 ml | $322.00 |