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Six4 Antibody (34-M) is a mouse monoclonal IgG1 antibody that detects Six4 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Six4, also known as AREC3, is a 760 amino acid nuclear protein that plays a crucial role in myogenesis and neurogenesis, as well as in the development of various organs. Six4 is part of the Six/Sine oculis homeobox family, characterized by a conserved DNA-binding domain that allows Six4 to regulate gene expression during development. The presence of a single Six domain in Six4, which functions as a homeobox DNA-binding motif, is essential for interaction with specific DNA sequences, thereby influencing the transcription of target genes. Notably, Six4 shares 90% sequence similarity with its mouse counterpart, indicating that both proteins likely exhibit similar DNA-binding properties and functional roles in developmental processes. The ability of Six4 to modulate gene expression is vital for proper cellular differentiation and organogenesis, making Six4 an important focus of study in developmental biology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Six4 Antibody (34-M) | sc-81984 | 100 µg/ml | $339.00 |