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Rhotekin Antibody (AA-18) is a mouse monoclonal IgG1 antibody that detects Rhotekin in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Rhotekin plays a crucial role in regulating the actin cytoskeleton, particularly in forming and maintaining stress fibers and focal adhesions, which are essential for cellular shape, motility, and division. Rhotekin acts as a downstream effector of the Rho GTPase signaling pathway, linking Rho to various cellular processes such as cytokinesis and cell adhesion. Rhotekin′s ability to interact with other proteins, including Rho and the serine/threonine kinases Rock-1 and Rock-2, highlights its importance in mediating Rho signaling effects. Rhotekin′s structural characteristics, which include a Rho-binding domain and a coiled-coil region, are vital for binding to Rho and facilitating downstream signaling events. Anti-Rhotekin antibody (AA-18) helps researchers gain insights into cytoskeleton dynamics and regulatory mechanisms governing cell behavior, making this tool valuable for studies in cell biology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rhotekin Antibody (AA-18) | sc-100426 | 100 µg/ml | $339.00 |