NEIL3 Antibody (2627C1b): sc-81331
- NEIL3 Antibody (2627C1b) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of NEIL3 of human origin
- recommended for detection of NEIL3 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NEIL3 Antibody (2627C1b). This work is in progress.
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NEIL3 Antibody (2627C1b) is a mouse monoclonal IgG1 antibody that detects NEIL3 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). NEIL3, also known as endonuclease VIII-like 3, plays a crucial role in the repair of oxidative DNA damage, which is vital for maintaining genomic stability and preventing mutations that can lead to various diseases, including cancer. NEIL3 (2627C1b) antibody targets a protein primarily localized in the nucleus, where NEIL3 participates in the base excision repair pathway by recognizing and excising damaged bases, although NEIL3′s glycosylase activity has been a subject of debate due to unique structural features. NEIL3 consists of 605 amino acids and contains both an FPG-type zinc finger and a RanBP2-type zinc finger, which are important for interaction with DNA and other proteins involved in the repair process. Notably, NEIL3 is expressed predominantly in thymus and testis tissues, highlighting potential significance in cellular processes specific to these organs. Anti-NEIL3 antibody (2627C1b) is an essential tool for researchers studying DNA repair mechanisms and the implications of oxidative stress in human health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NEIL3 Antibody (2627C1b) | sc-81331 | 100 µg/ml | $339.00 |