ITF-2/TCF4 Antibody (G-8): sc-515325
- ITF-2/TCF4 Antibody (G-8) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 187-209 near the N-terminus of ITF-2 of human origin
- recommended for detection of ITF-2 isoforms SEF2-1A and SEF2-1D of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-515325 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ITF-2/TCF4 Antibody (G-8) for WB applications. These reagents are now offered in bundles with ITF-2/TCF4 Antibody (G-8) (see ordering information below).
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SEE ALSO...
ITF-2 Antibody (G-8) is a mouse monoclonal IgG2a antibody that detects immunoglobulin transcription factor 2 (ITF-2) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ITF-2 plays a crucial role in the regulation of gene expression, particularly in muscle development, by binding to specific DNA motifs such as the immunoglobulin enhancer Mu-E5/KE5-motif and the Ephrussi-box (E-box) element found in SSTR2-INR, thereby acting as a transcriptional activator for muscle-specific genes. ITF-2 (G-8) antibody recognizes a protein that can form homo- or hetero-oligomers with other myogenic factors like myogenin and MyoD, allowing for a complex regulatory network that can either activate or repress transcription depending on the isoform present. This dynamic interaction is essential for proper muscle differentiation and development, highlighting ITF-2′s importance in both embryonic and adult tissues, including the heart, brain, and skeletal muscle. Anti-ITF-2 antibody (G-8) serves as an invaluable tool for researchers studying muscle biology and transcriptional control mechanisms.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ITF-2/TCF4 Antibody (G-8) | sc-515325 | 200 µg/ml | $322.00 | |||
ITF-2 Antibody (G-8): m-IgG Fc BP-HRP Bundle | sc-538773 | 200 µg Ab; 10 µg BP | $361.00 | |||
ITF-2 Antibody (G-8): m-IgGκ BP-HRP Bundle | sc-536443 | 200 µg Ab; 40 µg BP | $361.00 | |||
ITF-2 Antibody (G-8): m-IgG2a BP-HRP Bundle | sc-548402 | 200 µg Ab; 10 µg BP | $361.00 | |||
ITF-2 (G-8) Neutralizing Peptide | sc-515325 P | 100 µg/0.5 ml | $69.00 | |||
ITF-2 Antibody (G-8) X | sc-515325 X | 200 µg/0.1 ml | $322.00 |