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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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IQGAP3 Antibody (D-10) is a high quality monoclonal IQGAP3 antibody suitable for the detection of the IQGAP3 protein of mouse, rat and human origin. IQGAP3 Antibody (D-10) is available as both the non-conjugated anti-IQGAP3 antibody form, as well as multiple conjugated forms of anti-IQGAP3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson′s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Rated 1 von
TerribleUsed 100 ug of tissue on a western blot and could barely detect anything. Probed for GAPDH on this same membrane and it was fine so I know it wasn't the blot.
Rated 1 von
detect only IQ2overexpressed GFP-IQ1, 2, 3 in 293 cells. the Ab could detect only IQ2 weakly. there is weak non-specific band on 100kD.
1/1000 dil in 2% BSA TBST, o/n reaction.
Rated 5 von
Very good Western blot data of IQGAP3 expressionVery good Western blot data of IQGAP3 expression in Hep G2 whole cell lysate and human placenta tissue extract . -SCBT QC
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