EXOSC7 Antibody (E-12): sc-393685
- EXOSC7 Antibody (E-12) is a mouse monoclonal mouse IgG2a κ κ provided at 200 µg/ml
- raised against amino acids 133-291 mapping at the C-terminus of EXOSC7 of human origin
- recommended for detection of EXOSC7 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EXOSC7 Antibody (E-12) for WB applications. These reagents are now offered in bundles with EXOSC7 Antibody (E-12) (see ordering information below).
EXOSC7 Antibody (E-12) is a mouse monoclonal IgG2a antibody that detects EXOSC7 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EXOSC7, also known as p8, EAP1, RRP42, Rrp42p, or hRrp42p, is a crucial component of the exosome complex, which is essential for the degradation of unstable mRNAs containing AU-rich elements in their untranslated 3′ regions. EXOSC7 is localized in the nucleolus and is one of the six RNase-PH domain subunits that form a PNPase-like ring structure within the exosome, highlighting EXOSC7′s importance in RNA processing. Proper functioning of EXOSC7 is vital for the processing of 7S pre-RNA, which is a key step in the maturation of ribosomal RNA. By facilitating the degradation of defective or unnecessary RNA molecules, EXOSC7 plays a significant role in maintaining cellular RNA homeostasis, thereby influencing gene expression and overall cellular health. Anti-EXOSC7 antibody (E-12) is an invaluable tool for researchers studying RNA metabolism and the intricate mechanisms of gene regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EXOSC7 Antibody (E-12) | sc-393685 | 200 µg/ml | $322.00 | |||
EXOSC7 Antibody (E-12): m-IgG Fc BP-HRP Bundle | sc-538283 | 200 µg Ab; 10 µg BP | $361.00 | |||
EXOSC7 Antibody (E-12): m-IgGκ BP-HRP Bundle | sc-535862 | 200 µg Ab; 40 µg BP | $361.00 | |||
EXOSC7 Antibody (E-12): m-IgG2a BP-HRP Bundle | sc-548256 | 200 µg Ab; 10 µg BP | $361.00 |