Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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The death-associated protein 3 (DAP-3), is a nucleotide-binding protein that contains a potential P-loop motif. It is a positive mediator of programmed cell death; overexpressed intact full-length protein is required in order to induce apoptosis. DAP-3 functions downstream of its receptor signaling complex and its death promoting effects depend on caspase activity. It also interacts with the glucocorticoid receptor (GR), where its main interaction domain is the amino-terminal region, which acts in a dominant-negative fashion to protect cells from apoptosis. DAP-3 protein may also play a role in modulating the cytoplasmic GR/HSP 90 complex. It is conserved at the functional, as well as the structural level, and is ubiquitously expressed in highly proliferative epithelial compartments of various tissues. Unlike a number of other proteins, DAP-3 retains its mitochondrial localization during the induction of apoptosis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.