Bis(lauroyloxy)dioctyltin (CAS 3648-18-8)

Bis(lauroyloxy)dioctyltin (BLD) is an organotin compound with versatile applications across various industries. Derived from dioctyltin (DOT), Bis(lauroyloxy)dioctyltin consists of a central dioctyltin atom linked to two lauroyloxy groups. It serves as a vital component various industries, functioning as a stabilizer, plasticizer, preservative, biocide, and flame retardant. Additionally, Bis(lauroyloxy)dioctyltin has garnered significant attention in biotechnology, particularly in gene expression and delivery research. In the realm of biotechnology, Bis(lauroyloxy)dioctyltin has proven beneficial as both a gene expression enhancer and a gene delivery vector. Moreover, it has exhibited promise as a stabilizer for proteins like antibodies and as an inhibitor for polymerase chain reactions (PCR). While the precise mechanism of action remains partially elusive, it is postulated that the two lauroyloxy groups on the Bis(lauroyloxy)dioctyltin molecule interact with cell membranes, rendering them more permeable. This facilitated membrane permeability allows molecules such as DNA to enter the cell. Furthermore, Bis(lauroyloxy)dioctyltin′s interaction with specific proteins on the cell membrane is believed to induce the upregulation of certain genes.