Glabridin (CAS 59870-68-7)
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Glabridin is a chemical compound that functions as a tyrosinase inhibitor. It acts by inhibiting the activity of the enzyme tyrosinase, which is involved in the production of melanin. By doing so, Glabridin can effectively reduce the production of melanin in cells, making it useful for studying melanogenesis and pigmentation processes in experimental applications. At the molecular level, Glabridin interacts with the active site of tyrosinase, preventing the enzyme from catalyzing the conversion of tyrosine to melanin. This mechanism of action allows the investigation of the regulation of melanin production and its potential implications in various biological processes. In experimental applications, Glabridin′s role as a tyrosinase inhibitor provides insights into the molecular pathways involved in pigmentation and melanin synthesis.
Glabridin (CAS 59870-68-7) References
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- Glabridin, a bioactive component of licorice, ameliorates diabetic nephropathy by regulating ferroptosis and the VEGF/Akt/ERK pathways. | Tan, H., et al. 2022. Mol Med. 28: 58. PMID: 35596156
- Glabridin induces paraptosis-like cell death via ER stress in breast cancer cells. | Cui, X. and Cui, M. 2022. Heliyon. 8: e10607. PMID: 36158101
- Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice. | Chung, CL., et al. 2022. Int J Mol Sci. 23: PMID: 36232674
- Glabridin inhibits liver fibrosis and hepatic stellate cells activation through suppression of inflammation and oxidative stress by activating PPARγ in carbon tetrachloride-treated mice. | Zhang, L., et al. 2022. Int Immunopharmacol. 113: 109433. PMID: 36371863
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glabridin, 5 mg | sc-397145 | 5 mg | $130.00 | |||
Glabridin, 25 mg | sc-397145A | 25 mg | $520.00 |