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3-(Methylthio)propionic acid (CAS 646-01-5)

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Alternate Names:
4-Thiapentanoic acid
CAS Number:
646-01-5
Purity:
≥97%
Molecular Weight:
120.17
Molecular Formula:
C4H8O2S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-(Methylthio)propionic acid is a compound that functions as a precursor in the biosynthesis of methionine. It plays a role in the conversion of homocysteine to methionine, a process for protein synthesis and various metabolic functions. At the molecular level, 3-(Methylthio)propionic acid is involved in the transfer of a methyl group to homocysteine, leading to the formation of methionine. 3-(Methylthio)Propionic Acid reaction is catalyzed by specific enzymes, and the presence of 3-(Methylthio)propionic acid is necessary for the proper functioning of this pathway. Its mechanism of action involves participating in the methyl transfer process, ultimately contributing to the production of methionine.


3-(Methylthio)propionic acid (CAS 646-01-5) References

  1. How low pH can intensify beta-damascenone and dimethyl trisulfide production through beer aging.  |  Gijs, L., et al. 2002. J Agric Food Chem. 50: 5612-6. PMID: 12236686
  2. Alcohols, esters and heavy sulphur compounds production by pure and mixed cultures of apiculate wine yeasts.  |  Moreira, N., et al. 2005. Int J Food Microbiol. 103: 285-94. PMID: 16099313
  3. Pathways that produce volatile sulphur compounds from methionine in Oenococcus oeni.  |  Vallet, A., et al. 2008. J Appl Microbiol. 104: 1833-40. PMID: 18217924
  4. Purification of an alcohol dehydrogenase involved in the conversion of methional to methionol in Oenococcus oeni IOEB 8406.  |  Vallet, A., et al. 2009. Appl Microbiol Biotechnol. 82: 87-94. PMID: 18850096
  5. Use of 13C nuclear magnetic resonance and gas chromatography to examine methionine catabolism by lactococci.  |  Gao, S., et al. 1998. Appl Environ Microbiol. 64: 4670-5. PMID: 9835547
  6. GLC-mass-spectrometrical investigation of volatile constituents of wine: II. Thioether-Compounds of Wines  |  Schreier, P., Drawert, F., & Junker, A. 1974. Zeitschrift für Lebensmittel-Untersuchung und Forschung. 154: 279-284.
  7. Identification of 3 (methylthio) propionic acid as a blight-inducing toxin produced by Xanthomonas campestris pv. manihotis in vitro  |  Perreaux, D., Maraite, H., & Meyer, J. A. 1982. Physiological Plant Pathology. 20(3): 313-319.
  8. Detection of 3(methylthio) propionic acid in cassava leaves infected by Xanthomonas campestris pv. manihotis  |  Perreaux, D., Maraite, H., & Meyer, J. A. 1986. Physiological and molecular plant pathology. 28(3): 323-328.
  9. Oxidation of (carboxyalkyl) thiopropionic acid derivatives by hydroxyl radicals. Mechanisms and kinetics of competitive inter-and intramolecular formation of σ-and σ*-type sulfuranyl radicals  |  Bobrowski, K., Pogocki, D., & Schöneich, C. 1998. The Journal of Physical Chemistry A. 102(51): 10512-10521.
  10. Volatile sulphur compounds in wines related to yeast metabolism and nitrogen composition of grape musts  |  Moreira, N., Mendes, F., Pereira, O., De Pinho, P. G., Hogg, T., & Vasconcelos, I. 2002. Analytica Chimica Acta. 458(1): 157-167.
  11. Metabolite production and kinetics of branched-chain aldehyde oxidation in Staphylococcus xylosus.  |  Beck, H. C., Hansen, A. M., & Lauritsen, F. R. 2002. Enzyme and Microbial Technology. 31(1-2): 94-101.
  12. Insoluble grape material present in must affects the overall fermentation aroma of dry white wines made from three grape cultivars cultivated in Greece  |  Karagiannis, S., & Lanaridis, P. 2002. Journal of food science. 67(1): 369-374.
  13. Volatile compounds contribution of Hanseniaspora guilliermondii and Hanseniaspora uvarum during red wine vinifications  |  Moreira, N., Pina, C., Mendes, F., Couto, J. A., Hogg, T., & Vasconcelos, I. 2011. Food Control. 22(5): 662-667.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-(Methylthio)propionic acid, 10 g

sc-275849
10 g
$51.00