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4-Hydroxybenzaldehyde (CAS 123-08-0)

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Alternate Names:
p-Formylphenol
Application:
4-Hydroxybenzaldehyde is a chemical that maintains bactericidal activity when tested against certain bacteria strains
CAS Number:
123-08-0
Purity:
≥99%
Molecular Weight:
122.12
Molecular Formula:
C7H6O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Hydroxybenzaldehyde is a chemical that maintains bactericidal activity when tested against certain bacteria strains. It also displays antioxidant potential when analyzed through assay. It is also used as an extractant for sodium carbonate and hydroxyl group from acetate extract. Studies of 4-Hydroxybenzaldehyde have shown its impact on cellular growth and differentiation. As well as its effects on enzyme activity, protein expression, and gene expression.


4-Hydroxybenzaldehyde (CAS 123-08-0) References

  1. 4-Hydroxybenzaldehyde from Gastrodia elata B1. is active in the antioxidation and GABAergic neuromodulation of the rat brain.  |  Ha, JH., et al. 2000. J Ethnopharmacol. 73: 329-33. PMID: 11025174
  2. Simultaneous determination of p-hydroxybenzaldehyde, p-hydroxybenzyl alcohol, 4-(beta-D-glucopyranosyloxy)-benzyl alcohol, and sugars in Gastrodia elata blume measured as their acetylated derivatives by GC-MS.  |  Li, HX., et al. 2001. J Chromatogr Sci. 39: 251-4. PMID: 11396690
  3. Unusual 4-hydroxybenzaldehyde synthase activity from tissue cultures of the vanilla orchid Vanilla planifolia.  |  Podstolski, A., et al. 2002. Phytochemistry. 61: 611-20. PMID: 12423881
  4. Metabolism of l-Tyrosine to 4-Hydroxybenzaldehyde and 3-Bromo-4-Hydroxybenzaldehyde by Chloroplast-containing Fractions of Odonthalia floccosa (Esp.) Falk.  |  Manley, SL. and Chapman, DJ. 1979. Plant Physiol. 64: 1032-8. PMID: 16661087
  5. Spectrophotometric resolution of ternary mixtures of salicylaldehyde, 3-hydroxybenzaldehyde and 4-hydroxybenzaldehyde by the derivative ratio spectrum-zero crossing method.  |  Berzas Nevado, JJ., et al. 1992. Talanta. 39: 547-53. PMID: 18965415
  6. Synthesis and biological evaluation of novel 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors.  |  Yi, W., et al. 2010. Eur J Med Chem. 45: 639-46. PMID: 19932528
  7. The Effect of 4-hydroxybenzaldehyde on the γ-aminobutyric Acid Type A Receptor.  |  Zhang, J., et al. 2017. Malays J Med Sci. 24: 94-99. PMID: 28894409
  8. 4-Hydroxybenzaldehyde accelerates acute wound healing through activation of focal adhesion signalling in keratinocytes.  |  Kang, CW., et al. 2017. Sci Rep. 7: 14192. PMID: 29079748
  9. 4-Hydroxybenzaldehyde sensitizes Acinetobacter baumannii to amphenicols.  |  Shin, B., et al. 2018. Appl Microbiol Biotechnol. 102: 2323-2335. PMID: 29387955
  10. SAR of 4-Alkoxybenzoic Acid Inhibitors of the Trypanosome Alternative Oxidase.  |  Meco-Navas, A., et al. 2018. ACS Med Chem Lett. 9: 923-928. PMID: 30258542
  11. 4-Hydroxybenzaldehyde Restricts the Intracellular Growth of Toxoplasma gondii by Inducing SIRT1-Mediated Autophagy in Macrophages.  |  Lee, J., et al. 2020. Korean J Parasitol. 58: 7-14. PMID: 32145722
  12. 3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products.  |  Chen, KY., et al. 2021. Biomed J. 44: S258-S266. PMID: 35300947
  13. The predominance of endothelium-derived relaxing factors and beta-adrenergic receptor pathways in strong vasorelaxation induced by 4-hydroxybenzaldehyde in the rat aorta.  |  Loh, YC., et al. 2022. Biomed Pharmacother. 150: 112905. PMID: 35421787
  14. Design, Synthesis, and Spectroscopic Studies of Some New α-Aminophosphonate Analogues Derived from 4-Hydroxybenzaldehyde with Special Reference to Anticancer Activity.  |  Ali, OM., et al. 2022. Drug Des Devel Ther. 16: 2589-2599. PMID: 35965965
  15. Green Spectrophotometric Platforms for Resolving Overlapped Spectral Signals of Recently Approved Antiparkinsonian Drug (Safinamide) in the Presence of Its Synthetic Precursor (4-Hydroxybenzaldehyde): Applying Ecological Appraisal and Comparative Statistical Studies.  |  El-Sayed, HM., et al. 2022. J AOAC Int. 106: 26-33. PMID: 36214622

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Hydroxybenzaldehyde, 100 g

sc-256775
100 g
$26.00

4-Hydroxybenzaldehyde, 1 kg

sc-256775A
1 kg
$285.00

4-Hydroxybenzaldehyde, 5 kg

sc-256775B
5 kg
$734.00

4-Hydroxybenzaldehyde, 10 kg

sc-256775C
10 kg
$1336.00