Date published: 2025-9-24

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Glycerol trihexanoate (CAS 621-70-5)

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Alternate Names:
1,2,3-Tricaproylglycerol; Glycerol tricapronate;Tricaproin; Trihexanoin
CAS Number:
621-70-5
Purity:
≥95%
Molecular Weight:
386.52
Molecular Formula:
C21H38O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Glycerol trihexanoate, commonly known as trihexanoin, is a triglyceride where glycerol is esterified with three hexanoic acid chains. This chemical structure categorizes it as a medium-chain triglyceride (MCT), which is particularly notable for its distinct physical and chemical properties. In the realm of research, glycerol trihexanoate is extensively used in studies focusing on lipid metabolism and energy production, especially given its medium-chain fatty acids that are metabolized differently from long-chain fatty acids. This compound is also a valuable tool in the study of lipid digestion and absorption processes due to its rapid breakdown and absorption rates in comparison to longer-chain triglycerides. Glycerol trihexanoate′s utility extends into the field of materials science, where it is explored for its potential in producing biodegradable polymers and surfactants. Its ability to act as a plasticizer and its solubility properties make it an interesting candidate for the creation of environmentally friendly materials. Additionally, its relatively low melting point and unique solubility characteristics are advantageous in the formulation of cosmetics and personal care products, where researchers investigate its applications as a non-toxic and biodegradable alternative to traditional chemical components. Techniques such as chromatography and spectroscopy are commonly employed to study its composition, breakdown, and interactions at the molecular level, providing insights crucial for industrial applications where sustainable and efficient lipid utilization is key.


Glycerol trihexanoate (CAS 621-70-5) References

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  2. Temperature- and pressure-dependent densities, self-diffusion coefficients, and phase behavior of monoacid saturated triacylglycerides: toward molecular-level insights into processing.  |  Greiner, M., et al. 2012. J Agric Food Chem. 60: 5243-9. PMID: 22500590
  3. Ultrasound-assisted biosynthesis of novel methotrexate-conjugates.  |  Noro, J., et al. 2018. Ultrason Sonochem. 48: 51-56. PMID: 30080579
  4. Toxicity of medium chain fatty acids to Penicillium crustosum Thom and their detoxification to methyl ketones[J].  |  Hatton P V, Kinderlerer J L. 1991. Journal of Applied Microbiology,. 70(5): 401-407.
  5. Characterization of the cuticular lipids of the larvae and adults of the pecan weevil, Curculio caryae[J].  |  Espelie K E, Payne J A. 1991. Biochemical systematics and ecology,. 19(2): 127-132.
  6. Information on the composition of fats from their high‐resolution13C nuclear magnetic resonance spectra[J].  |  Gunstone F D. 1993. Journal of the American Oil Chemists' Society. 70(4): 361-366.
  7. Evaporation and flow properties of several hydrocarbon oils[J].  |  Karis T E, Nagaraj H S. 2000. Tribology transactions,. 43(4): 758-766.
  8. Saturated vapor pressures and enthalpies of evaporation of esters of glycerol and lower carboxylic acids[J].  |  Maslakova A S, Krasnykh E L, Levanova S V. 2010. Russian Journal of Physical Chemistry A,. 84(2): 163-168.
  9. Polylactides with "green" plasticizers: Influence of isomer composition[J].  |  Arias V, Höglund A, Odelius K. 2013. Journal of Applied Polymer Science. 130(4): 2962-2970.
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Glycerol trihexanoate, 1 ml

sc-215079
1 ml
$77.00

Glycerol trihexanoate, 5 ml

sc-215079A
5 ml
$265.00