Date published: 2025-12-5

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6-O-α-Maltosyl-β-cyclodextrin (CAS 104723-60-6)

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Application:
6-O-α-Maltosyl-β-cyclodextrin is a compound used in cholesterol studies
CAS Number:
104723-60-6
Molecular Weight:
1459.26
Molecular Formula:
C54H90O45
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-O-alpha-Maltosyl-beta-cyclodextrin (Mal-betaCD) is a cellular cholesterol modifier which can form a soluble inclusion complex with cholesterol and is much less cytotoxic to human erythrocytes and Caco-2 cells. It has been used to assess the effects of the cholesterol inclusion complex on cellular cholesterol levels as well as investigate the enantioseparation of catechin and epicatechin. 6-O-α-Maltosyl-β-cyclodextrin removes cellular cholesterol forming inclusion complexes, while 6-O-α-Maltosyl-β-cyclodextrin-induced lack of cellular cholesterol is replenished by the addition of CLM without cytotoxicity. Cholesterol reduction by 6-O-α-Maltosyl-β-cyclodextrin abolishes the mRNA and protein expression of ABCA1 and ABCG1, but not of P-gp.


6-O-α-Maltosyl-β-cyclodextrin (CAS 104723-60-6) References

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  4. Characterization of the Supermolecular Structure of Polydatin/6-O-α-Maltosyl-β-cyclodextrin Inclusion Complex.  |  Liu, B., et al. 2015. J Food Sci. 80: C1156-61. PMID: 25916244
  5. Characterization of complexes between phenethylamine enantiomers and β-cyclodextrin derivatives by capillary electrophoresis-Determination of binding constants and complex mobilities.  |  Wahl, J., et al. 2017. Electrophoresis. 38: 1188-1200. PMID: 28130905
  6. Role of 6-O-α-maltosyl-β-cyclodextrin in lysosomal cholesterol deprivation in Npc1-deficient Chinese hamster ovary cells.  |  Okada, Y., et al. 2018. Carbohydr Res. 455: 54-61. PMID: 29172126
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-O-α-Maltosyl-β-cyclodextrin, 5 g

sc-214380
5 g
$168.00