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6-O-alpha-Maltosyl-beta-cyclodextrin (Mal-betaCD) is a cellular cholesterol modifier which can form a soluble inclusion complex with cholesterol and is much less cytotoxic to human erythrocytes and Caco-2 cells. It has been used to assess the effects of the cholesterol inclusion complex on cellular cholesterol levels as well as investigate the enantioseparation of catechin and epicatechin. 6-O-α-Maltosyl-β-cyclodextrin removes cellular cholesterol forming inclusion complexes, while 6-O-α-Maltosyl-β-cyclodextrin-induced lack of cellular cholesterol is replenished by the addition of CLM without cytotoxicity. Cholesterol reduction by 6-O-α-Maltosyl-β-cyclodextrin abolishes the mRNA and protein expression of ABCA1 and ABCG1, but not of P-gp.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-O-α-Maltosyl-β-cyclodextrin, 5 g | sc-214380 | 5 g | $168.00 |