Molecular structure of Meglumine, CAS Number: 6284-40-8
Meglumine (CAS 6284-40-8)
Alternate Names:
N-Methyl-D-glucamine; N-Methylglucamine
Application:
Meglumine is an amino sugar compound
CAS Number:
6284-40-8
Purity:
99%
Molecular Weight:
195.21
Molecular Formula:
C7H17NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Meglumine is a derivative of sugar alcohol, mannitol. It has been used as an antiprotozoal compound for leischmaniasis. It is a excipient used as a stabilizer, solubilizer, and dispersant in a variety of formulations. It acts as a surfactant and a chelating agent. Meglumine is also used as a contrast agent in X-ray imaging and Magnetic Resonance Imaging (MRI). It may act to have an effect on the metabolism of glucose, cholesterol, and triglycerides. In vitro studies have been conducted using Meglumine to evaluate the solubility, stability, and bioavailability of different compounds.
Meglumine (CAS 6284-40-8) References
- The metabolism and excretion of methylglucamine (N-methyl-D-glucamine) in the rat. | Ryan, AJ., et al. 1976. Life Sci. 19: 1925-7. PMID: 1004138
- Adsorption Behavior of Metasilicate on N-Methyl d-Glucamine Functional Groups and Associated Silicon Isotope Fractionation. | Wang, W., et al. 2016. Langmuir. 32: 8872-81. PMID: 27499230
- Development and validation of a new HPLC-MS method for meglumine impurity profiling. | Martano, C., et al. 2018. J Pharm Biomed Anal. 149: 517-524. PMID: 29175747
- TRPM4 mediates a subthreshold membrane potential oscillation in respiratory chemoreceptor neurons that drives pacemaker firing and breathing. | Li, K., et al. 2021. Cell Rep. 34: 108714. PMID: 33535052
- Temperature dependence of membrane ion conductance analyzed by using the amphiphilic anion 5/6-carboxyfluorescein. | Bramhall, J., et al. 1987. Biochemistry. 26: 6330-40. PMID: 3427008
- Obesity-induced astrocyte dysfunction impairs heterosynaptic plasticity in the orbitofrontal cortex. | Lau, BK., et al. 2021. Cell Rep. 36: 109563. PMID: 34407401
- Gadopentetate meglumine activates mast cells to cause IgE-independent allergic reactions both in vitro and in vivo. | Liu, X., et al. 2022. Int Immunopharmacol. 106: 108602. PMID: 35131571
- Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule. | He, X., et al. 2022. Pharm Res. 39: 2263-2276. PMID: 35836038
- Synthesis, characterization and application of a novel sorbent, glucamine-modified MCM-41, for the removal/preconcentration of boron from waters | Kaftan, Ö., Açıkel, M., Eroğlu, A. E., Shahwan, T., Artok, L., & Ni, C. 2005. Analytica chimica acta. 547(1): 31-41.
- Calorimetric properties and solubility in five pure organic solvents of N-methyl-d-glucamine (meglumine) | Svard, M., Hjorth, T., Bohlin, M., & Rasmuson, Å. C. 2016. Journal of Chemical & Engineering Data. 61(3): 1199-1204.
- Preparation of calcium-phosphate cements with high compressive strength using meglumine as a water reducer | Sawamura, T., Okuyama, M., Maeda, H., Obata, A., & Kasuga, T. 2016. Journal of the Ceramic Society of Japan. 124(3): 223-228.
- Synthesis, crystallisation and thermodynamics of two polymorphs of a new derivative of meglumine: 1-(2, 2, 3-trimethyl-1, 3-oxazolidin-5-yl)-butane-1, 2, 3, 4-tetrol | Svärd, M., Krishna, G. R., & Rasmuson, Å. C. 2018. CrystEngComm. 20(1): 88-95.
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GAP1m.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Meglumine, 50 g | sc-205383 | 50 g | $50.00 | |||
Meglumine, 250 g | sc-205383A | 250 g | $89.00 | |||
Meglumine, 500 g | sc-205383B | 500 g | $140.00 | |||
Meglumine, 1 kg | sc-205383C | 1 kg | $280.00 |