D-Aspartic acid (CAS 1783-96-6)

D-Aspartic acid is an endogenous NMDA receptor agonist with similar activity to the L-isomer. It is also a non-metabolizable substrate for EAA uptake systems. It modulates melatonin synthesis in the pineal gland. D-Aspartic acid (D-Asp) is a naturally occurring amino acid present in the human body, as well as in other mammals, plants, and certain bacteria. Classified as a non-essential amino acid, it isn′t necessary to obtain it from the diet since the body can synthesize it from other amino acids. Within the realm of biology, D-Aspartic acid holds a role in various processes, including protein synthesis, metabolism, and neurotransmission. Moreover, it plays a part in regulating hormones, such as testosterone and growth hormone. Despite the ongoing research, the precise mechanism of action of D-Aspartic acid remains partially understood. However, it is believed to act as a neuromodulator, influencing the activity of neurotransmitters and hormones in intricate ways. Additionally, D-Aspartic acid is thought to interact with the NMDA receptor, a specific type of glutamate receptor that has implications in learning and memory, among other physiological processes.